In the game between the Indianapolis Colts and Kansas City Chiefs on Sunday, Nov. 23 at 1 p.m. ET, our projection model expects the Colts to come away with the victory. Seeking predictions on the final score, spread, and point total, too? Find a complete game projection below.
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Chiefs vs. Colts Game Info and TV Channel
- When: Sunday, November 23, 2025 at 1 p.m. ET
- Where: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
- TV: CBS
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
- Live Stream: Watch this game on Paramount+ (Regional restrictions may apply)
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Listen to the game on 96.5 The Fan
Chiefs vs. Colts Odds and Betting Info
- Spread favorite: Chiefs (-3.5)
- Moneyline: Chiefs (-185), Colts (+154)
- Total: 49.5 points
Chiefs vs. Colts Prediction
- Pick ATS: Colts (+3.5)
- Pick OU: Under (49.5)
Prediction:
Colts 25 - Chiefs 24
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Chiefs vs. Colts Betting Insights
- The Chiefs have put together a 5-5-0 ATS record so far this year.
- The Colts have compiled a 6-4-0 ATS record so far this year.
- Kansas City has covered the spread three times this season (3-2 ATS) when playing as at least 3.5-point favorites.
- Indianapolis has been an underdog by 3.5 points or more this year once, and failed to cover the spread.
- In the Chiefs' 10 games this season, the combined scoring has gone over the point total three times.
- The Colts and their opponent have combined to hit the over six out of 10 times this year.
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